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Bioinformatics Institute


Software tools


Bioinformatics Institute staff, students, and affiliates have contributed to the development of many resources, listed below.

BEAST2


BEAST (Bayesian Evolutionary Analysis Sampling Trees) is a cross-platform program for Bayesian MCMC analysis of molecular sequences. This tool was developed through a collaborative project by Professor Alexei Drummond.

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DNA Surveillance


DNA Surveillance is a system used for the identification of species using phylogenetic analyses

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DTWave


DTWave is a tool for analysis of sound sequences. It was developed by Dr Louis Ranjard.

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DTWave_cluster - Unsupervised Sound Classification using Artificial Neural Network


DTWave_cluster performs automatic classification of a set of WAV sound files. Typically, DTWave_cluster can be used for the automatic classification of any bioacoustics signal when no prior information about clustering is available. It relies on the C program DTWave (DTWave) for sound alignment and average computation and uses an unsupervised artificial neural network clustering algorithm.

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GeneSetDB


GeneSetDB is a comprehensive meta-database with associated gene set enrichment analysis statistical tools, which integrates a large number of other biological databases for gene set analysis.

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MelanomaDB


MelanomaDB is a web interface to a large database of melanoma genomic information. It is a specific application of the GeneSetDB web tool. Using MelanomaDB, users can identify the intersection and union between sets of genes including personal lists of genes.

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Melanoma Profiler


Melanoma Profiler is a web application for cancer genomic research which is accessed through Illumina's BaseSpace portal. It performs a comparative variant analysis across tumor and germline samples, comparing modified genes and pathways to those in a curated set of known melanoma tumor samples.

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Pebble


Pebble (Phylogenetics, Evolutionary Biology, and Bioinformatics in a moduLar Environment) is a phylogenetic analysis application which provides tools for analysis and simulation of serially sampled sequence data. It was developed by Professor Allen Rodrigo and Matthew Goode.

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Phyloland


The R package Phyloland implements a model of space colonization mapped onto a phylogeny, it aims at testing for limited dispersal and ecological competitive exclusion in a Bayesian MCMC statistical phylogeographic framework.

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PhyML


PhyML is a phylogeny software based on the maximum-likelihood principle. This tool was developed through a collaborative project by Dr Stephane Guindon.

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shiny_cuffdiff


shiny_cuffdiff is a Shiny/R interface used to visualise the outputs from the Tuxedo workflow (Tophat2 > Cufflinks > Cuffdiff), which is a cuffdiff SQL database. Plots are created using the gene names or XLOC number.

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Species Delimitation plugin for Geneious


The Species Delimitation plugin for the Geneious bioinformatics software is an exploratory tool that allows users to assess putative species in phylogenetic trees.

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SplitsTree4


SplitsTree4 is an application for computing unrooted phylogenetic networks from molecular sequence data.

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Squint v1.02


Squint is a multiple sequence alignment editor. It is an extension of the alignment editor availaible in Squint. This application was developed by Professor Allen Rodrigo and Matthew Goode. 

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