Bioinformatic and systems biology methods can be used to help understand disease. A major challenge facing medical science at present is the integration of vast and rapidly growing volumes of information into a holistic understanding of disease. Most projects in this area involve collaboration between specialists in compuational biology, applied mathematics, statistics, genetics, as well as pathologists, physicians and surgeons.
Simply combining `omics information from different sources, or simply generating mathematical models of the molecular aspects of a disease are unsatisfying, no matter how elegant the methods used are! Instead, evaluation of this type of research by laboratory experiments or clinical trials is required to translate `omics information into improved biological understanding or clinical practice.